Post-Traumatic Stress Disorder and Chronic Fatigue Syndrome-Like Illness Among Gulf War Veterans: A Population-based Survey of 30,000 Veterans

Authors
Kang, H. K. Natelson, B. H. Mahan, C. M. Lee, K. Y. Murphy, F. M.
Publication year
2003
Citation Title
Post-traumatic stress disorder and chronic fatigue syndrome-like illness among Gulf War veterans: A population-based survey of 30,000 Veterans.
Journal Name
American Journal of Epidemiology
Journal Volume
157
Issue Number
2
Page Numbers
141-148
DOI
10.1093/aje/kwf187
Summary
Gulf War Veterans and non-Gulf War Veterans completed surveys in 1995 about their experiences and health status. This study examined the association between deployment, deployment stress, and symptoms of posttraumatic stress disorder (PTSD) and Chronic Fatigue Syndrome. Those who had deployed were more likely to experience PTSD and Chronic Fatigue Syndrome symptoms, and deployment stress was associated with greater PTSD symptoms.
Key Findings
Veterans who had been deployed during the Gulf War were three times more likely to experience PTSD symptoms and nearly five times more likely to experience Chronic Fatigue Syndrome symptoms than those who had not deployed.
Among Gulf War Veterans, PTSD prevalence increased as stress intensity increased; this pattern was not evident for Chronic Fatigue Syndrome symptoms.
Several demographic characteristics were also associated with PTSD symptoms: those with symptoms were more likely to be female, older, non-White, enlisted, and in the Army and National Guard.
Veterans with Chronic Fatigue Syndrome symptoms were more likely younger, single, enlisted, in the Army or Marines, and in the Reserves.
Implications for Program Leaders
Incorporate information into curricula about Chronic Fatigue Syndrome symptoms, treatment, and resources; this information could educate Service members and their families about warning signs, risks, and treatment options
Enhance curriculum to provide information about stress management, healthy coping, and use of support networks as protective factors to minimize risk for PTSD symptoms
Disseminate information regarding possible symptoms of mental health problems Service members may face after deployment and where individuals and families can find help for those problems
Implications for Policy Makers
Recommend adding screening for Chronic Fatigue Syndrome into Service members’ post-deployment screening
Recommend integrating education on physical health conditions associated with deployment into existing service delivery systems for military families
Recommend education for service providers around the possible effects of deployment on Service members’ families
Methods
Participants completed a mail-in or telephone survey in 1995 about their deployment experiences and PTSD and Chronic Fatigue Syndrome symptoms.
Deployment and demographic data were provided by the Defense Manpower Data Center.
Particpant data were selected based on a random sampling method in order to have a representative sample of Service members regarding gender, service branch, and component.
Participants
This study used a stratified probability sample comprised of Gulf War Veterans (n = 11,441) and non-Gulf War Veterans (n = 9,476) to represent the population.
Of those who were Gulf War Veterans, 81% were men, 74% were White, 53% were married, 86% were enlisted, and 63% Army.
Of those who were not Gulf War Veterans, 78% were men, 75% were White, 56% were married, 81% were enlisted, and 63% Army.
Limitations
The scope of this study was limited to only PTSD and Chronic Fatigue Syndrome symptoms. It is unclear what associations may exist for other similar problems.
Mail-in and phone surveys have inherent limitations which may have affected the validity of the participants’ responses.
This study is cross-sectional and no findings regarding causation can be determined from these data.
Avenues for Future Research
Examine PTSD, Chronic Fatigue Syndrome, and stress among Service members who have been deployed in more recent combat deployments (e.g., Iraq, Afghanistan)
Explore how PTSD and Chronic Fatigue Syndrome symptoms affect other aspects of Service members’ lives, such as employment (e.g., being able to gain and maintain civilian work) and relationships (e.g., marital quality, family relationships)
Conduct a study to examine these variables among Service members who are in treatment compared to those who are not in treatment
Design Rating
3 Stars - There are few flaws in the study design or research sample. The flaws that are present are minor and have no effect on the ability to draw conclusions from the data.
Methods Rating
3 Stars - The definitions and measurement of variables is done thoroughly and without any bias and conclusions are drawn directly from the analyses performed.
Limitations Rating
3 Stars - There are only minor factors that limit the ability to extend the results to an entire population.
Focus
Multiple Branches
Target Population
Population Focus
Military Component
Abstract
The authors estimated the prevalence of post-traumatic stress disorder (PTSD) and illness resembling chronic fatigue syndrome (CFS) in the entire population of Gulf War and non-Gulf-War veterans. They also evaluated the relation between the extent of deployment-related stress and the risk of either PTSD or CFS. In 1995–1997, the authors conducted a health survey in which these two symptom-based medical diagnoses in a population-based sample of 15,000 Gulf War veterans representing four military branches and three unit components (active, reserve, and National Guard) were compared with those of 15,000 non-Gulf veteran controls. Gulf War veterans, compared with non-Gulf veteran controls, reported significantly higher rates of PTSD (adjusted odds ratio = 3.1, 95% confidence interval: 2.7, 3.4) and CFS (adjusted odds ratio = 4.8, 95% confidence interval: 3.9, 5.9). The prevalence of PTSD increased monotonically across six levels of deployment-related stress intensity (test for trend: p < 0.01), while the prevalence of CFS rose only at the low end of the stress spectrum. While deployment related stress could account for the higher risks of both PTSD and CFS, additional factor(s) unique to the Gulf environment may have contributed to the risk of CFS among Gulf War veterans.
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