Type
Summary
The first dose of live attenuated measles-containing vaccines is associated with an increased risk of febrile seizures 7 to 10 days following immunization among 12- to 23-month-old children. The combination measles, mumps, rubella, and varicella vaccine is associated with a 2-fold increased risk of febrile seizures 7 to 10 days following immunization compared with the separately administered measles, mumps, and rubella and varicella vaccines. It is unknown whether the magnitude of these increased risks depends on age at immunization.
Citation
Rowhani-Rahbar, A., Fireman, B., Lewis, E., Nordin, J., Naleway, A., Jacobsen, S. J.,& Klein, N. P. (2013). Effect of age on the risk of fever and seizures following immunization with measles-containing vaccines in children. JAMA pediatrics, 167(12), 1111-1117. doi:10.1001/jamapediatrics.2013.2745.